Partikula Featured in BioCentury Emerging Company Profiles

Partikula delivering chemotherapeutics into mitochondria of cancer cells Partikula: Mitochondrial delivery By Lev Osherovich Senior Writer Published on Monday, March 17, 2014 Partikula LLC is developing nanoparticles that have size and charge optimized to deliver therapeutic payloads into mitochondria, beginning with two lead programs that aim to disrupt cancer metabolism by using the technology to deliver chemotherapeutic and cytotoxic agents. Mitochondria drive cellular metabolism. The intracellular organelles are particularly active in cancers, which require substantial amounts of energy to grow. However, selectively hitting mitochondrial targets has proven challenging because drugs must cross multiple membranes. Read more at...